MBS microplates are available in 96-well and 384-well, and all plates have the same frame, with a polypropylene foil with 96 or 384 wells. 96-well plates may be used with volumes from 5-20 or 2-5 microliter while 384-well plates can be used with volumes from 2-5 microliter. All microplates have wells with a wall thickness of less than 50 microns. The wells are sealed simultaneously, but individually, using a heat sealer and a proprietary anvil. The wells can be sealed with aluminum or polyester backed polypropylene foil. Both foils can be pierced with MBS pipettips.