The Savanna RVP4 Assay (Respiratory Viral Panel-4) is a rapid, multiplexed real-time PCR test intended for use with the Savanna instrument for the simultaneous qualitative detection and differentiation of influenza A (Flu A), influenza B (Flu B), respiratory syncytial virus (RSV), and SARS-CoV-2 RNA isolated from human nasal or nasopharyngeal swabs in media obtained from patients with signs and symptoms of respiratory tract infection. Consisting of a self-contained, single-use assay cartridge, the Savanna RVP4 Assay requires no sample or reagent preparation prior to inserting the cartridge into the Savanna instrument. All sample and reagent preparation, nucleic acid extraction and amplification, and real-time detection of viral RNA is fully automated and completed by the Savanna instrument in approximately 22 minutes.